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researchers establish basis of development of vertebrate limb muscles in cartila




the development of limb muscle has been well studied in most land dwelling vertebrates such as humans and modern research models. in these species, muscle precursors, or cells that will form limb muscle, travel to the limb bud, a location in the developing embryo where they multiply and form muscle ...



not all muscle building supplements are equal




image: professor kevin tipton is pictured. view more credit: university of stirlingpopular muscle building supplements, known as branched-chain amino acids (bcaa) are ineffective when taken in isolation, according to new research from the university of stirling.the study, involving the universitie...



seven ways muscle makes us healthier




working out with weights means different things to different people. it can be the buzz that comes with lifting a big barbell off the ground – or a way to make clothes fit better.but to professor rob newton, director of the exercise medicine research institute at edith cowan university, building m...



muscle fibers alone can't explain sex differences in bird song




male birds tend to be better singers than females—but does the basis for this difference lie in the brain or in the syrinx, the bird equivalent of our larynx? the researchers behind a new study from the auk: ornithological advances analyzed the muscle fibers in the syrinxes of male and female bird...



h&h question of the week: how do i add topline to a good-doer without feeding mu




spillers' equine nutritionist clare barfoot provides one h&h forum user with some helpful advice on how to add topline onto a horse who is a good-doerq:“my horse is a good doer. not overweight but has a good little grass belly. his ribs are still able to be felt. “he also lacks lots of muscle. a...



muscle fibers alone can't explain sex differences in bird song




male birds tend to be better singers than females--but does the basis for this difference lie in the brain or in the syrinx, the bird equivalent of our larynx? the researchers behind a new study from the auk: ornithological advances analyzed the muscle fibers in the syrinxes of male and female birds...



1 amvrka's 'american muscle' video: watch




los angeles-based duo 1 amvrka (pronounced “one america”) have set out to bring some light to the country amid its rather tough political climate, creating music with meaningful and a blend of hip-hop, folk-rock, country and pop. their latest song, "american muscle," does just that and bill...



muscle growth finding may assist with cancer treatment




monash university's biomedicine discovery institute (bdi) researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer. the approach, jointly ...



common strength 'genes' identified for first time




common genetic factors that influence muscle strength in humans have been identified for the first time in a study led by researchers from the university of cambridge and published today in nature communications. the researchers used data on hand grip strength from more than 140,000 participants in ...



understanding the epidemiology of sarcopenia throughout the lifecourse




sarcopenia is an age-related syndrome which is characterised by progressive and generalised loss of muscle mass and strength. how prevalent is sarcopenia? as there is a lack of consensus in the operational definition used to characterized the disorder, estimates vary widely in different clinical set...



new understanding of how muscles work




muscle malfunctions may be as simple as a slight strain after exercise or as serious as heart failure and muscular dystrophy. a new technique developed at mcgill now makes it possible to look much more closely at how sarcomeres, the basic building blocks within all skeletal and cardiac muscles, work...



chimpanzee 'super strength' and what it might mean in human muscle evolution




since at least the 1920s, anecdotes and some studies have suggested that chimpanzees are "super strong" compared to humans, implying that their muscle fibers, the cells that make up muscles, are superior to humans.



gene therapy helps dogs with muscle dystrophy, humans next?




researchers have used gene editing to reverse symptoms in dogs of duchenne muscular dystrophy (dmd)—a muscle-wasting and life-shortening disease that affects one in 5,000 baby boys.



fighting myocardial infarction with nanoparticle tandems




via a cannula introduced into the infarction area, the cells loaded with magnetic nanoparticles are injected into the damaged heart muscle tissue of the mouse. credit: dr. annika ottersbach/uni bonnhow can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells?...



can combined exercise and nutritional intervention improve muscle mass and funct




although progressive muscle loss is a natural part of ageing, sarcopenia is generally identified when muscle mass and muscle function falls below defined thresholds. sarcopenia's impact can be enormous as it affects mobility, balance, risk of falls and fractures, and overall ability to perform tasks...



how non-muscle cells find the strength to move




figure: visualization of myosin ii filament stacks (yellow) with cross-linking protein alpha-actinin-1 (blue) in fibroblast cells using structured illumination microscopy. myosin ii filaments alternate with apha-actinin enriched domains along actin stress fibre. credits: mechanobiology institute, si...



chimpanzee 'super strength' and what it might mean in human muscle evolution




image: umberger says there are nearly 100 years of accounts suggesting that chimpanzees must have intrinsically superior muscle fiber properties compared with humans, yet there had been no direct tests of... view more credit: umass amherstamherst, mass. - since at least the 1920s, anecdotes and so...



ca2+, the intercellular signal in arterioles




vasoconstriction must be balanced with vasodilation, particularly in the arterioles that supply tissues with blood. endothelial cells protrude through holes in the internal elastic lamina in arterioles to make contact with vascular smooth muscle cells. gap junctions are present at these sites where ...



change in protein production essential to muscle function




image: this is dr. thomas a. cooper. view more credit: baylor college of medicineresearchers at baylor college of medicine have shed light on the process that guides the maturation of newborn muscles into adult, fully functional organs. in mice, they determined that a group of genes involved in ca...



h&h question of the week: what should i feed my horse to develop topline muscle?




spillers' equine nutritionist clare barfoot provides one h&h forum user with some helpful advice on how to feed her weak horse for better muscle developmentq: “feeding a weak horse to support muscle development: i’m not going to say what i’m currently feeding him, because i’m interested in c...



nih and collaborators identify the genomic cause for carey-fineman-ziter syndrom




image: the graphic depicts normal myoblasts (early muscle cells with a single nucleus) fusing together to form muscle cells with more than one nucleus. the cascade is disrupted in carey-fineman-ziter syndrome,... view more credit: darryl leja, nhgrian international team of researchers has identifi...



heart failure therapy hope as drug blocks deadly muscle scarring




a potential treatment to prevent deadly muscle scarring that contributes to chronic heart failure has been uncovered by scientists.the therapy could also prevent scarring of the skeletal muscles we use to move our arms and legs, a cause of long-term disabilities. the treatment works by targeting mol...



columbia engineering researchers make soft robotics breakthrough with new artifi




researchers at columbia engineering have made a breakthrough in soft robotics that is said to have solved a long standing issue in creating untethered soft robots. the goal of these soft robots is to mimic the action and movements of natural biological systems. the research team was led by hod lipso...



atomic resolution of muscle contraction




at the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. new electron cryomicroscopy images with unprecedented resolution taken by researchers at osaka university reveal unexpectedly large conformational changes in the myosin molecule during the pull. these ...



atomic resolution of muscle contraction




image: this is the architecture of skeletal muscle formed by regular arrays of myosin and actin filaments. view more credit: osaka universityat the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. new electron cryomicroscopy images with unprecedented resol...