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study shows adipose stem cells may be the cell of choice for therapeutic applica




an international team of researchers, funded by morris animal foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.researchers at the university of guelph, university of western ...



scientists rejuvenate blood by reprogramming cells




like it or not, your body gradually loses its capacity for producing blood as you age -- that's why immune deficiencies, leukemia and other blood conditions become more likely with time. scientists may have found a way to turn back the clock, though. they've found a way to rejuvenate blood by reprog...



study shows stem cells fiercely abide by innate developmental timing




the mystery of what controls the range of developmental clocks in mammals—from 22 months for an elephant to 12 days for a opossum—may lie in the strict time-keeping of pluripotent stem cells for each unique species.



super resolution imaging helps determine a stem cell's future




scientists at rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible.



stem cell reprogramming factor controls change in cellular energy generation




university of tsukuba-led researchers explored the function of the reprogramming factor klf4 in production of induced pluripotent stem cells (ipscs). klf4 was shown to bind upstream of the tcl1 target gene, which controls a metabolic change in energy generation during the acquisition of cellular plu...



research uncovers potential health risks of travel to mars




winston-salem, n.c. - march 8, 2017 - sending a manned mission to mars requires more than a powerful launch rocket. prep work also includes learning how a three-year space flight could affect the human body. with funding from the national aeronautics and space administration (nasa), researchers at t...



making metabolically active brown fat from white fat-derived stem cells




image: tissue engineering brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. view more credit: mary ann liebert, inc., publishersnew rochelle, ny, march 3, 2017--researchers have demonstr...



see how zika infection changes a human cell




the zika virus taking hold of the inner organelles of human liver and neural stem cells has been captured via light and electron microscopy. in cell reports on february 28, researchers in germany show how the african and asian strains of zika rearrange the endoplasmic reticulum and cytoskeletal arch...



cells communicate better when not squeezed together, research shows




scientists are beginning to realize that many cellular behaviors, such as metastasizing cancer cells moving through the body or wound healing, aren't random events, but the result of coordinated actions by cells.



organ-on-a-chip model offers insights into premature aging and vascular disease




image: physiological strain induces a contractile phenotype in primary smooth muscle cells. view more credit: joao ribas, brigham and women's hospitalhutchinson-gilford progeria syndrome (hgps) is an extremely rare genetic condition that causes premature and accelerated aging. recently, researchers...



scientists wage fight against aging bone marrow stem cell niche




image: this molecular image shows immunofluorescence staining in the soft spongy section of trabecular bone in the femur of a young mouse. red staining reveals the abundant presence of the protein... view more credit: university of ulmcincinnati - as people get older so do the hematopoietic stem ce...



cells communicate better when not squeezed together, research shows




cells communicate by exchanging molecules, allowing either short- and long-range communication. purdue university biophysicist andrew mugler discovered that, contrary to his hypothesis, long-range communication for the cells was more accurate purdue university . credit: ken ritchiescientists are beg...



organ-on-a-chip model offers insights into premature aging and vascular disease




photograph of the microfluidic channel showing the media inlet and outlet. credit: joao ribas, brigham and women's hospitalhutchinson-gilford progeria syndrome (hgps) is an extremely rare genetic condition that causes premature and accelerated aging. recently, researchers have been able to generate ...



cell 'stickiness' could indicate metastatic potential




how strongly tumor cells adhere to the surrounding tissue could indicate the likelihood that cancer will spread to other parts of the body, according to a study published february 28 in biophysical journal. using a spinning disc device, the researchers found that tumor cells characterized by weak ad...



organ-on-a-chip model offers insights into premature aging and vascular disease




hutchinson-gilford progeria syndrome (hgps) is an extremely rare genetic condition that causes premature and accelerated aging. recently, researchers have been able to generate induced pluripotent stem cells from patients with hgps to better understand the mechanisms of aging and look for new treatm...



a new role for an old immune cell may lead to novel therapies for infection and




a new study has identified a previously undescribed role for a type of unconventional t cell with the potential to be used in the development of new therapies for infection and cancer.the study, published today in nature communications, shows that gamma delta t cells are able to generate immunologic...



saving brain cells from stroke




researchers from the university of iowa carver college of medicine and the university of miami miller school of medicine have shown that a neuroprotective compound tested in rats provides two-pronged protection for brain cells during stroke and improves physical and cognitive outcomes in the treated...



scientists discover how obesity stops 'guardian immune cells' from doing their j




scientists have uncovered the physiological mechanics underlying inflammation and obesity by tracking the actions of 'guardian immune cells' in response to changes in diet. they believe their work may herald a new era of research now that they have new therapeutic targets to prevent and control obes...



scientists discover new mechanism that leads to inflammation in rheumatoid arthr




new research findings published in the journal of leukocyte biology, suggest that synovial cd4+ t cells that produce il-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients. understanding the mechanisms of inflammation in rheumatoid arthritis is imp...



scientists engineering cells to eat deadly bacteria




researchers at the johns hopkins university are working to engineer single-cell organisms that will seek out and eat bacteria that are deadly to humans. their work combines the fields of biology and engineering in an emerging discipline known as synthetic biology.although the work is still in its in...



world-first synthetic receptor mimics how cells 'talk' to the world around them




researchers from the university of bristol have found a way to mimic the way cells in living organisms 'talk' to the world around them by creating a world-first synthetic receptor which can respond to chemical signals just like its natural equivalent.



new structural studies reveal workings of a molecular pump that ejects cancer dr




sometimes cells resist medication by spitting it back out. cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. researchers at the rockefeller university have shed new light on a molecular pump that makes this possible, by determining its ...



can math help explain our bodies -- and our diseases?




image: stephen smale, ph.d., and indika rajapakse, ph.d., have teamed up to create mathematical models that aim to explain how tissues emerge from the information contained in the genome. view more credit: university of michiganann arbor, mi - what makes a cluster of cells become a liver, or a musc...



can math help explain our bodies—and our diseases?




using advanced mathematics, researchers hope to create models of biological systems that can inform our understanding of normal development and disease. credit: university of michiganwhat makes a cluster of cells become a liver, or a muscle? how do our genes give rise to proteins, proteins to cells,...



a vulnerability in triple-negative breast cancer could improve treatment outcome




image: alex toker is an investigator at the ludwig center at harvard. view more credit: ludwig cancer researchmarch 2, 2017, new york -- a team of researchers led by alex toker of the ludwig center at harvard has discovered a metabolic weakness in triple-negative breast cancer (tnbc) cells that may...