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special focus issue of immunotherapy explores the use of allergen-specific immun




immunotherapy, a leading medline-indexed journal, published by future science group, has released a special focus issue providing insights into the latest advances in allergen immunotherapy covering both environmental and food allergies, with the aim of directing the improvement and optimization of ...



special issue of future medicinal chemistry explores immunotherapy edit article




the field of immunotherapy is moving forward at an unprecedented rate, and a range of therapeutic approaches are now used in clinical practice, often with outstanding success. cancer immunotherapy, in particular, has recently come of age, with many of the breakthrough drugs showing significant advan...



gold nanostars and immunotherapy vaccinate mice against cancer




by combining an fda-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, duke university researchers improved the efficacy of both therapies in a proof-of-concept study using mice.



advancing cancer immunotherapy with computer simulations and data analysis




image: this is a scanning electron micrograph of a human t lymphocyte (also called a t cell) from the immune system of a healthy donor. immunotherapy fights cancer by supercharging the... view more credit: niaidthe body has a natural way of fighting cancer - it's called the immune system, and it i...



wistar scientists develop novel immunotherapy technology for prostate cancer




philadelphia -- (aug. 17, 2017) -- a study led by scientists at the wistar institute describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic dna to directly encode protective antibodies against a cancer specific protein. this is the first application of...



dna mutations shed in blood predicts response to immunotherapy in patients with




in a first-of-its-kind study, university of california san diego school of medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies."we can help predict response to immunotherapy by measuring the number of...



australian breakthrough sees children 'cured' of peanut allergy




a small clinical trial of a new immunotherapy treatment has seen more than two-thirds of children with a peanut allergy cured. australian researchers have made a breakthrough in the treatment of deadly peanut allergies in children.a small clinical trial conducted at the murdoch children's research i...



scientists light the way for immune system to attack cancer




the science behind harnessing the immune system to fight cancer is complicated, but a university of rochester medical center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors. in a study published by the online journal nature communicati...



targeting immune cells that help tumors stay hidden could improve immunotherapy




image: vignali lab 3-d microscopic image of a tumor shows tregs (green), blood vessels (red) and tumor matrix (blue). link to high-res version... view more credit: pitt health sciences/vignali labpittsburgh, june 15, 2017 - researchers at university of pittsburgh school of medicine and upmc have d...



flaws in a tumor's genetic mending kit drive treatment response to immunotherapy




image: an image of a t-cell is shown. view more credit: photo courtesy of robbie b. mailliard, phd, university of pittsburgh graduate school of public healthin an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' g...



patients' immune system may influence effectiveness of cancer immunotherapy




washington, april 2, 2017 - higher or lower levels of certain immune cells in cancer patients may be associated with how well they respond to immunotherapy, according to preliminary results of a study conducted by researchers at the university of pittsburgh cancer institute (upci). the findings will...



free c3d regulates immune checkpoint blockade and enhances anti-tumor immunity




image: when the c3d vaccine was added to a tumor, the cancer cells began to die (right). tumor cells not given the vaccine continued to grow. view more credit: michigan medicineann arbor, michigan -- in the body, anti-cancer immunity is immobilized by stealth cancer forces. but a natural de-immobi...



scientists discover surprising immune cell activity that may be limiting immunot




ann arbor, michigan -- researchers have uncovered a surprising process within a key immune cell that may help explain the limitations of immunotherapy as a cancer treatment.treg cells work within the immune system to suppress immune function. it's a normal process: t cells fight an infection and whe...



immunotherapy: a new therapy may cure kids of peanut allergy




in a long-term study of the latest treatment for peanut allergy, scientists in australia report that an immune-based therapy helped children allergic to peanuts eat them without reactions for four years.the study, published in the journal lancet child & adolescent health, follows up on children enro...



liver tumor growth in mice slowed with new chemo-immunotherapy treatment




image: university of missouri school of medicine researchers have developed a new treatment that combines chemotherapy and immunotherapy to significantly slow tumor growth in mice. the team includes (from left) guangfu... view more credit: justin kelley/mu healthcolumbia, mo. (feb. 28, 2017) -- hep...



benefits of using droplet digital pcr for measuring immunotherapy response highl




hercules, calif. -- july 11, 2017 -- new research demonstrating the clinical potential of bio-rad's droplet digital pcr (ddpcr) technology to measure patient response to immunotherapy was presented at the american society of clinical oncology (asco) annual meeting in june.monitoring patient response...



cox-2 inhibitors may reverse ido1-mediated immunosuppression in some cancers




bottom line: in preclinical studies, tumors that consitutively expressed the protein indoleamine 2,3-dioxygenase (ido1) responded to the cyclooxygenase-2 (cox-2) inhibitor celecoxib (celebrex) and had improved infiltration of certain subsets of t cells, making them more likely to respond to anti-pd1...



purifying cells to treat disease




various cell therapies involve injecting a specific cell type into a patient. these include, for example, bone marrow transplants and some types of immunotherapy that use t-cells (a white blood cell involved in immunity) to help fight cancer. credit: royaltystockphoto / 123rfvarious cell therapies i...



th17 cells could facilitate wider clinical use of adoptive immunotherapy




image: cancer immunologist dr. chrystal m. paulos and jacob s. bowers of the medical university of south carolina were both authors on the jci insight article. view more credit: medical university of south carolinamedical university of south carolina (musc) investigators report that long-term expan...



ludwig scientists share research at the society for immunotherapy of cancer annu




november 6, 2017, new york - ludwig cancer research has released the scope of its participation at the 2017 society for immunotherapy of cancer (sitc) annual meeting in national harbor, maryland, november 8-12. ludwig scientists will share data at the conference from preclinical and clinical studies...



ludwig scientists share research at the society for immunotherapy of cancer annu




november 6, 2017, new york - ludwig cancer research has released the scope of its participation at the 2017 society for immunotherapy of cancer (sitc) annual meeting in national harbor, maryland, november 8-12. ludwig scientists will share data at the conference from preclinical and clinical studies...



expanding the reach of therapeutic antibodies




a group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. the details will be published in the sept. 1 issue of the journal of biological chemistry.



for cancer patients with hiv, immunotherapy appears safe




seattle -- nov. 7, 2017 -- a new category of immunotherapies called checkpoint inhibitors that has been highly effective against many different cancers appears safe to use in patients with both advanced malignancies and hiv, a population excluded from earlier trials of such therapies, according to a...



immune cells the missing ingredient in new bladder cancer treatment




new research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.the study finds that checkpoint immunotherapy, which is designed to activate the immune system, is not effective on some bladder cancers because there are no immun...



immunotherapy target suppresses pain to mask cancer




image: sensory neurons from human dorsal root ganglia, a collection of nerves and neurons near the top of the spinal cord, show red for pd-1, a binding site for immunotherapies against... view more credit: ru-rong ji lab, duke universitydurham, n.c. -- once hailed as a breakthrough in cancer treat...