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researchers target protein that protects bacteria's dna 'recipes'




image: dps (in green) densely compacts dna (blue strands), but this doesn't have any detectable effect on gene expression. rna polymerase (pink) is still able to bind to the dna and... view more credit: university of rochester illustration / elio abbondanzieribacteria cause many serious illnesses,...



nanoparticles can help scientists brighten their research—but they also can thro




credit: acsgold nanoparticles brighten the fluorescent dyes researchers use to highlight and study proteins, bacteria and other cells, but the nanoparticles also introduce an artifact that makes the dye appear removed from the target it's illuminating. now, a university of michigan team has determin...



how pathogenic bacteria prepare a sticky adhesion protein




researchers at harvard medical school, the university of california, san francisco, and the university of georgia have described how the protein that allows strep and staph bacteria to stick to human cells is prepared and packaged. the research, which could facilitate the development of new antibiot...



new insight into the molecular weapons of the plant microbiome




like all organisms, plants are associated with bacterial communities in which helpful and harmful bacteria compete for dominance. among the weaponry of these warring bacteria are molecular syringes that some bacteria can use to inject toxins into others. in a study published in the feb. 2 issue of t...



microbial murder mystery solved | eurekalert! science news




image: this cartoon, entitled "monkey wrench ", portrays how granzyme b targets and disrupts protein synthesis in bacteria. here, bacterial protein synthesis is depicted as a processing line where granzyme b --... view more credit: artwork by sylvie shaffer of the wistar institute.immune cells cal...



saliva plays a role in the body's defense against traveler's diarrhea




(boston)--researchers have identified a protein in saliva (histatin-5) that protects the body from traveler's diarrhea.the findings, available online in the journal of infectious diseases, may lead to the development of new preventive therapies for the disease. traveler's diarrhea is an inconvenienc...



secretin protein with a crown




bacteria are consummate survivalists. they are aided in this by their ability to assimilate dna from their surroundings, which allows them to constantly acquire new characteristics. researchers at the max planck institute of biophysics and goethe university in frankfurt have now gained new insights ...



molecular cuisine for gut bacteria




molecular cuisine for gut bacteria. credit: aleksandra krolik / emblembl scientists report in nature microbiology on the nutritional preferences and growth characteristics of 96 diverse gut bacterial strains. their results will help scientists worldwide advance the understanding of the gut microbiom...



new insight into the molecular weapons of the plant microbiome




like all organisms, plants are associated with bacterial communities in which helpful and harmful bacteria compete for dominance. among the weaponry of these warring bacteria are molecular syringes that some bacteria can use to inject toxins into others. in a study published in the feb. 2 issue of t...



microbiome: why your eyes might be full of bacteria




the human body is teeming with bacteria, and a lot of it is good for you. scientists have shown that the microbiome—a community of bacteria that live in the gut and on other places like skin—can protect people against other disease-carrying bugs.now, a new study published by researchers at the n...



melting bacteria to decipher antibiotic resistance




e. coli bacteria colored in heat gradient. credit: aleksandra krolik / emblwith antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. embl researchers have adapted an existing technique to study the melting behaviour of proteins so that it can be u...



melting bacteria to decipher antibiotic resistance




image: e. coli bacteria colored in heat gradient. view more credit: aleksandra krolik / emblwith antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. embl researchers have adapted an existing technique to study the melting behaviour of proteins ...



new crispr-cas9 tool edits both rna and dna precisely




a depiction of how the nmecas9 protein can be used as part of the crispr technique to edit single-stranded rna. credit: university of michigan, yan zhang laboratorya tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that...



virus's multipronged attack on bacteria points to new ways to fight infection




researchers have uncovered how a virus uses a two-pronged attack against a single protein to kill bacteria.



how bacteria manipulate plants




attack at the protein front: xanthomonas bacteria causes disease in tomato and pepper plants and injects harmful proteins into plant cells. researchers from martin luther university halle-wittenberg (mlu), the university of bonn, the university of freiburg and the leibniz institute of plant biochemi...



how bacteria manipulate plants | eurekalert! science news




attack at the protein front: xanthomonas bacteria cause diseases in tomato and pepper plants and inject harmful proteins into plant cells. researchers from martin luther university halle-wittenberg (mlu), the university of bonn, the university of freiburg and the leibniz institute of plant biochemis...



scientists unravel the structure of common bacterial wall-building protein




the wall that surrounds bacteria to shield them from external assaults has long been a tantalizing target for drug therapies. indeed, some of modern medicine's most reliable antibiotics disarm harmful bacteria by disrupting the proteins that build their protective armor.



enzymes from dangerous bacteria turn into important tools for protein chemistry




philipp ochtrop from umeå university has worked on a project to turn the two enzymes ankx and lem3 from the disease causing bacteria legionella pneumophila into a valuable tool for the chemical modification of proteins. this new approach for protein functionalization can enable scientists to invest...



anti-crispr proteins decrease off-target side effects of crispr-cas9




the anti-crispr protein (red on right) mimics dna, binding in the site where the cutting enzyme cas9 typically grips the target dna (left) before it cuts. but the anti-crispr protein doesn't let go, essentially killing cas9's gene editing ability. credit: fuguo jiang, uc berkeleycrispr-cas9 gene edi...



researchers identify protein target to halt citrus tree disease




university of florida researchers may have come a step closer to finding a treatment for a disease called huanglongbing, or citrus greening, that has been decimating citrus trees in the state. in work published this week in msphere, an open access journal from the american society for microbiology, ...



four-billion-year-old 'fossil' protein resurrected in bacteria protects them fro




this figure shows two possible outcomes from a viral attempt to infect the cell. on the left, the virus binds to the bacterium, injects its genetic info, and stops because it can't recruit the needed proteins. on the right, the virus binds to the cell, injects the genetic info, recruits the proteins...



don't sweat it: scientists identify key step in production of bo




if this surprisingly hot british summer has you fighting off unwelcome armpit aromas, you'll be pleased to learn that science has just brought us a step closer to blocking body odour (bo).researchers have unravelled a key part of the molecular process by which armpit bacteria produce the most pungen...



"monkey wrench" molecule jams tuberculosis protein




image of the protein tryptophan synthase created using diffraction data from argonne's advanced photon source. the inhibitor binds between the reaction sites in the protein, represented here by the orange and blue pockets. credit: argonne national laboratorytuberculosis has now surpassed hiv worldwi...



researchers studying how to disrupt bacteria to better treat infections




bacteria are everywhere. and despite widespread belief, not all bacteria are "bad." however, to combat those that can cause health issues for humans, there has been an over-reliance on the use of antibiotics - so much so, that many of them are now proving ineffective due to bacteria developing incre...



bacterial supermachine reveals streamlined protein assembly line




the bacterial expressome. in bacteria, the machine that reads dna to turn it into a message and the machine that translates the message into protein are combined into single complex or "supermachine." in humans and other organisms, these machines are distinct. that bacteria link them has important i...