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genome editing in human cells




new techniques in molecular biology that enable targeted interventions in the genome are opening up promising new possibilities for research and application. the ethical and legal ramifications of these methods, known as "genome editing" and "genome surgery," need to be discussed throughout society,...



new limits to functional portion of human genome reported




an evolutionary biologist at the university of houston has published new calculations that indicate no more than 25 percent of the human genome is functional. that is in stark contrast to suggestions by scientists with the encode project that as much as 80 percent of the genome is functional.



new limits to functional portion of human genome reported




image: evolutionary biologist dan graur has published new calculations that indicate no more than 25 percent of the human genome is functional. view more credit: university of houstonan evolutionary biologist at the university of houston has published new calculations that indicate no more than 25...



study redefines hpv-related head and neck cancers




much of what we thought we knew about the human papilloma virus (hpv) in hpv-related head and neck cancers may be wrong, according to a newly published study by virginia commonwealth university (vcu) researchers that analyzed data from the human cancer genome atlas. head and neck cancers involving h...



synthesizing the human genome from scratch




for the past 15 years, synthetic biologists have been figuring out how to synthesize an organism's complete set of dna, including all of its genes. they've tackled the genomes of microbes, but now one large consortium has its sights set on the human genome. the cover story in chemical & engineering ...



scientists assemble zika virus mosquito genome from scratch




image: a multi-institutional team has sequenced the genome of the mosquito that transmits the zika virus uisng a new way to sequence the genome of an organism entirely from scratch, dramatically... view more credit: robert langa team spanning baylor college of medicine, rice university, texas child...



nhgri oral history collection features influential genomics researchers




image: this is a timeline of our genomics history. view more credit: ernesto del aguila iii, nhgria collection of oral history videos released today by the national human genome research institute (nhgri) features candid conversations with pioneering genomics researchers and an interactive discussi...



fully sequenced deer genome made publicly available




researchers at baylor college of medicine have played a leading role in sequencing the whole genome of the common white-tailed deer, which has recently been made public by the national center for biotechnology information. the deer genome has the potential to provide insights into bone behavior, mor...



research decoding the first deep-sea mussel genome published




a joint research led by hong kong baptist university (hkbu) and the hong kong university of science and technology (hkust) has assembled the 1.64 gigabytes genome of a deep-sea mussel, which is roughly equivalent to 50% of the size of human genome. this is the first decoded genome among all deep-sea...



for anorexia nervosa, researchers implicate genetic locus on chromosome 12




may 12, 2017 chapel hill, nc - a landmark study led by unc school of medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also be metabolic underpinnings to this potentially deadly illness.the study, which is the most powerful genetic study...



decoding the genome's cryptic language




image: artistic rendering of rna-dna interactions. a 3-d structure of tightly coiled dna is depicted as the body of a dragon in chinese myth. interacting rnas are depicted as hairs, whiskers... view more credit: victor o. leshykbioengineers at the university of california san diego have developed a...



new analysis of rare argentinian rat unlocks origin of the largest mammalian gen




image: this is the red vizcacha rat, a rare species found in argentina. view more credit: mcmaster universityhamilton, july 12, 2017 -new biological information gleaned from the red vizcacha rat, a native species of argentina, demonstrates how genomes can rapidly change in size.researchers from mc...



the proteins that domesticated our genomes




epfl scientists have carried out a genomic and evolutionary study of a large and enigmatic family of human proteins, to demonstrate that it is responsible for harnessing the millions of transposable elements in the human genome. the work reveals the largely species-specific gene-regulatory networks ...



new whole genome amplification method reduces biases introduced by other methods




(phys.org)—a team of researchers working at harvard university has developed a new whole-genome amplification method that outperforms other methods currently being used. in their paper published in the journal science, the team describes their technique and how well it performed when used to measu...



german researchers sequence rye genome for first time




in this july 25, 2008 file photo rye spikes are pictured in a field near bad muenstereifel, western germany, during the morning sun. scientists in germany have for the first time mapped the entire genome of rye, a cereal known for its hardy properties. researchers from the technical university of mu...



the future of genomics: brainstorm health




with the advent of crispr, a new way to edit dna, the field of genomic technology has never been more exciting. the implications have yet to be seen, but scientists could theoretically snip out a person's genetic risk for disease. but it's also never been a more anxiety-inducing time. some experts a...



basf licenses crispr-cas9 genome-editing technology from the broad institute




basf has announced that it has reached a global licensing agreement with the broad institute of mit and harvard for the use of crispr-cas9 genome-editing technology to improve products in agricultural and industrial microbiology applications.the technology advances genome editing because it has the ...



study finds large chromosomal swaps key to banana domestication




credit: cc0 public domainbananas are one of the most important staple crops of the tropics, transported with great care over great distances to satisfy the world's appetite. and today, with more than half the world's bananas coming from a single, cavendish variety, they may increasingly become susce...



fish study shows important genome interactions in animal cells




a salt water marsh, where f. heteroclitus naturally occur. individuals used in the study were collected in marshes in mantoloking, nj. inset: a male f. heteroclitus. credit: douglas crawfordin a new study, researchers at the university of miami (um) rosenstiel school of marine and atmospheric scienc...



firefly gene illuminates ability of optimized crispr-cpf1 to efficiently edit hu




scientists on the florida campus of the scripps research institute (tsri) have improved a state-of-the-art gene-editing technology to advance the system's ability to target, cut and paste genes within human and animal cells—and broadening the ways the crispr-cpf1 editing system may be used to stud...



ongoing natural selection against damaging genetic mutations in humans




the survival of the human species in the face of high rates of genetic mutations has remained an important problem in evolutionary biology. while mutations provide a source of novelty for the species, a large fraction of these genetic changes can also be damaging. a newborn human is estimated to hav...



the first sequencing of a channel catfish genome




a fish named "coco" is at the center of the first genome sequence for any catfish species.



why do shorter men go bald more often?




image: stefanie heilmann-heimbach and markus nöthen from the institute of human genetics at the university of bonn, in collaboration with colleagues, identified over 60 alterations in the human genome that increase... view more credit: © photo: andreas stein/institut für humangenetikshort men ma...



spider silk genes used in… venom gland?




enlargenational park serviceshare this storyaccording to the national human genome research institute, about 300 different species have had their entire genomes sequenced. us, obviously, but also rats, puffer fish, fruit flies, sea squirts, roundworms, chickens, dogs, yeast, honey bees, gorillas, ch...



nuclear architecture emerges at the awakening of the genome




a depiction of the double helical structure of dna. its four coding units (a, t, c, g) are color-coded in pink, orange, purple and yellow. credit: nhgrithe dna molecules in each one of the cells in a person's body, if laid end to end, would measure approximately two metres in length. remarkably, how...