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largest psoriasis meta analysis to date yields new genetic clues - Search

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largest psoriasis meta-analysis to date yields new genetic clues




image: elder's team has identified 16 additional genetic markers, which will help researchers get closer to understanding how -- and why -- psoriasis develops. view more credit: michigan medicineit's one of the most common immune-mediated diseases in the u.s., causing red, patchy and scaly marks o...



sun pharma's partner almirall applies for psoriasis drug approval in europe




almirall’s filing with ema includes efficacy and safety data from the pivotal phase iii clinical trials (resurface 1 and 2) that included over 1,800 patients across more than 200 clinical sites. jesper jensen, executive vice president - biologics & dermatology, sun pharma, added, “not all people...



pitt study provides clues to relationship between schizophrenia and rheumatoid a




pittsburgh, feb. 24, 2017 - an in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the university of pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at low...



tweaking inflammation | eurekalert! science news




image: tweak regulates inflammation in atopic dermatitis and psoriasis. left: normal skin. middle: skin inflammation in atopic dermatitis. right: blocking tweak reduces skin inflammation in atopic dermatitis. view more credit: courtesy of dr. daniel sidler, la jolla institute for allergy and immun...



genetic analysis reveals patterns of migration of early bantu speaking people




(phys.org)—an international team of researchers has learned more about the migration history of early bantu speaking people (bsp) in africa by conducting a genetic analysis of over 2000 people living on the continent today. in their paper published in the journal science, the team describes their ...



for anorexia nervosa, researchers implicate genetic locus on chromosome 12




may 12, 2017 chapel hill, nc - a landmark study led by unc school of medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also be metabolic underpinnings to this potentially deadly illness.the study, which is the most powerful genetic study...



crop yields beyond 2012: yen five years on




in 2012 adas, with other industry organisations, jointly initiated a yield enhancement network or ‘yen’ to try to kick-start an upward trend in uk grain yields. 2012 was a bad year for uk cereal producers with smaller yields than for twenty years.  an industry review was published into possible...



new study quadruples known genetic risk factors for fuchs dystrophy




bottom line: researchers discovered three novel genetic mutations associated with fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.journal in which the study was published: nature communicationsauthor: sudha k. iyengar, phd, professor of epidemiology an...



a kidney disease's genetic clues are uncovered




new york, ny (march 6, 2017)--researchers have uncovered new genetic clues to understanding iga nephropathy (igan), or berger's disease, an autoimmune kidney disease and a common cause of kidney failure. the findings are relevant to igan as well as other diseases with similar underlying molecular de...



genetic findings in 'type 1.5' diabetes may shed light on better diagnosis, trea




image: struan f.a. grant, ph.d., is a genomics researcher at children's hospital of philadelphia. view more credit: children's hospital of philadelphiaresearchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic i...



hubble discovery of runaway star yields clues to breakup of multiple-star system




as british royal families fought the war of the roses in the 1400s for control of england's throne, a grouping of stars was waging its own contentious skirmish—a star wars far away in the orion nebula.



brain anatomy differs in people with 22q genetic risk for schizophrenia, autism




a ucla study characterizes, for the first time, brain differences between people with a specific genetic risk for schizophrenia and those at risk for autism, and the findings could help explain the biological underpinnings of these neuropsychiatric disorders.the research, published may 23 in the jou...



why nature is one of farming's best assets




around 7,000 species of plants have been eaten by humans at one time or another. in many cases, the wild relatives of these foods still occur in the natural environment, including oats, beet, carrot, parsnip, radish and asparagus. these wild relatives of crops are invaluable to our food security, as...



first genetic radiography of the wheat from 21 mediterranean countries used to m




a team of spanish scientists, with the participation of the university of granada, has carried out the first durum wheat genetic, phenotypic and geographic adaptation study to date. durum wheat is mostly used for the production of pasta and semolina in the mediterranean area.



hair strands could reveal lifestyle secrets of criminals (video)




image: emerging hair analysis techniques could help reveal vital lifestyle information about crime suspects. view more credit: glen p. jackson, ph.d.san francisco, april 4, 2017 -- hair fiber analysis, a forensic crime tool with a questionable past, could soon have a brighter future thanks to the d...



many genetic changes can occur early in human development




image: this is dr. pengfei liu holding human dna treated with fluorescent dyes prepared for copy number variant analysis. view more credit: baylor college of medicinethe genetic material of an organism encodes the instructions that guide its development. these codes are not written in stone; they c...



oyster farming to benefit from new genetic screening tool




oyster farmers are set to benefit from a new genetic tool that will help to prevent disease outbreaks and improve yields.the technology will enable hatcheries to rapidly assess the genetic make-up of their oysters, so they can select animals with desirable characteristics from which to breed.scienti...



from skin to brain: stem cells without genetic modification




buffalo, n.y. -- a discovery, several years in the making, by a university at buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in th...



improving connections for spatial analysis




a statistical model that accounts for common dependencies in spatial data yields more realistic results for studies of temperature, wind and pollution levels.



a closer look at the meta 2 ar headset




meta has also been working hard on building out its custom operating system, as well as figuring out how to develop a new language of gestures for augmented reality. i had a chance to test out the shipping version of the meta 2 at sxsw, and while it's still not perfect, it's the best ar experience i...



genetic analysis better explains how uterine cancers resist treatment




researchers have charted the complex molecular biology of uterine carcinosarcoma, a rare and aggressive gynecologic cancer, according to a study published on march 13 in cancer cell. using this new collection of genomic information, physicians will be better able to determine the specific genetic fi...



even in death, indigenous border crossers marginalized




the number of undocumented border crossers who died trying to migrate into arizona from mexico rose dramatically after 1994 (red arrow), when border patrol policy changed to increasingly militarize and patrol the safest, easiest passages across the us-mexico border, funneling migrants to more diffic...



test soil and manure to boost grass yields




farmers could significantly boost grass yields and quality by making better use of soil and manure analysis, according to experts speaking at the grassland & muck event.around 40-45% of uk grassland is deficient in potash, and more than half has a ph below six, dramatically reducing the efficiency o...



what silver fir adna can tell us about neolithic forests




a new technique makes it possible to cost-effectively analyse genetic material from fossil plant and animal remains. researchers from the swiss federal institute for forest, snow and landscape research wsl and the universities of lausanne and bern have used this technique to examine the dna of silve...



study reveals 10,000 years of genetic continuity in northwest north america




image: researchers are analyzing dna from ancient individuals found in southeast alaska, coastal british columbia, washington state and montana. a new genetic analysis of some of these human remains finds that... view more credit: graphic by julie mcmahon, university of illinoischampaign, ill. -- a...