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scientists discover how obesity stops 'guardian immune cells' from doing their j




scientists have uncovered the physiological mechanics underlying inflammation and obesity by tracking the actions of 'guardian immune cells' in response to changes in diet. they believe their work may herald a new era of research now that they have new therapeutic targets to prevent and control obes...



scientists rejuvenate blood by reprogramming cells




like it or not, your body gradually loses its capacity for producing blood as you age -- that's why immune deficiencies, leukemia and other blood conditions become more likely with time. scientists may have found a way to turn back the clock, though. they've found a way to rejuvenate blood by reprog...



genetic variant linked to overactive inflammatory response




researchers at cardiff university have discovered that genetic variation is the reason why some immune systems overreact to viruses.previous research had already revealed that a gene called ifitm3 influences how sensitive people are to the influenza virus, with a variant form of the gene making cell...



study shows adipose stem cells may be the cell of choice for therapeutic applica




an international team of researchers, funded by morris animal foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.researchers at the university of guelph, university of western ...



a new role for an old immune cell may lead to novel therapies for infection and




a new study has identified a previously undescribed role for a type of unconventional t cell with the potential to be used in the development of new therapies for infection and cancer.the study, published today in nature communications, shows that gamma delta t cells are able to generate immunologic...



scientists stimulate immune system, stop cancer growth




a chemical found in tumors may help stop tumor growth, according to a new study.researchers at the university of illinois at chicago report that increasing expression of a chemical cytokine called light in mice with colon cancer activated the immune system's natural cancer-killing t-cells and caused...



asthmatics less able to fight off flu




people with asthma are likely to have worse symptoms when they get the flu because they have weaker immune systems, new southampton research has shown.a study led by dr ben nicholas, of the university of southampton, and published in the journal of allergy and clinical immunology, assessed lung samp...



cells communicate better when not squeezed together, research shows




scientists are beginning to realize that many cellular behaviors, such as metastasizing cancer cells moving through the body or wound healing, aren't random events, but the result of coordinated actions by cells.



sex differences in brain activity alter pain therapies




image: this is dr. anne murphy, co-author on the study and associate professor in the neuroscience institute at georgia state university. view more credit: georgia state universityatlanta--a female brain's resident immune cells are more active in regions involved in pain processing relative to male...



cells communicate better when not squeezed together, research shows




cells communicate by exchanging molecules, allowing either short- and long-range communication. purdue university biophysicist andrew mugler discovered that, contrary to his hypothesis, long-range communication for the cells was more accurate purdue university . credit: ken ritchiescientists are beg...



cell 'stickiness' could indicate metastatic potential




how strongly tumor cells adhere to the surrounding tissue could indicate the likelihood that cancer will spread to other parts of the body, according to a study published february 28 in biophysical journal. using a spinning disc device, the researchers found that tumor cells characterized by weak ad...



allergies? probiotic combination may curb your symptoms, new study finds




as we head into allergy season, you may feel less likely to grab a hanky and sneeze. that's because new university of florida research shows a probiotic combination might help reduce hay fever symptoms, if it's taken during allergy season.many published studies have shown a probiotic's ability to re...



saving brain cells from stroke




researchers from the university of iowa carver college of medicine and the university of miami miller school of medicine have shown that a neuroprotective compound tested in rats provides two-pronged protection for brain cells during stroke and improves physical and cognitive outcomes in the treated...



researchers identify how inflammation spreads through the brain after injury




researchers have identified a new mechanism by which inflammation can spread throughout the brain after injury. this mechanism may explain the widespread and long-lasting inflammation that occurs after traumatic brain injury, and may play a role in other neurodegenerative diseases.the findings were ...



the dreaded "man cold" is real! here's how to heal it.




it's time to talk about that serious malady, the dreaded man cold. the sniffle that turns into a hacking cough that becomes a "raging" fever that turns into the inability to throw away used tissues or even change the tv channel by oneself. luckily, this extremely common disease (which, in my house, ...



study shows stem cells fiercely abide by innate developmental timing




the mystery of what controls the range of developmental clocks in mammals—from 22 months for an elephant to 12 days for a opossum—may lie in the strict time-keeping of pluripotent stem cells for each unique species.



scientists identify a key barrier to proliferation of insulin-producing cells.




image: this is rohit kulkarni, m.d., ph.d., senior investigator at joslin diabetes center, and professor of medicine at harvard medical school. view more credit: john soaresboston - (march 9, 2017) - if you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body t...



scientists discover new mechanism that leads to inflammation in rheumatoid arthr




new research findings published in the journal of leukocyte biology, suggest that synovial cd4+ t cells that produce il-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients. understanding the mechanisms of inflammation in rheumatoid arthritis is imp...



scientists engineering cells to eat deadly bacteria




researchers at the johns hopkins university are working to engineer single-cell organisms that will seek out and eat bacteria that are deadly to humans. their work combines the fields of biology and engineering in an emerging discipline known as synthetic biology.although the work is still in its in...



world-first synthetic receptor mimics how cells 'talk' to the world around them




researchers from the university of bristol have found a way to mimic the way cells in living organisms 'talk' to the world around them by creating a world-first synthetic receptor which can respond to chemical signals just like its natural equivalent.



new insights on how pathogens escape the immune system




our immune system has various ways to deal with threats from the outside like pathogens. one of the defence mechanisms is a process called autophagy. 'you can imagine autophagy as the vacuum cleaner of the cell', says nirmal robinson, leading scientist of the study. 'it keeps the cell clean by clear...



new structural studies reveal workings of a molecular pump that ejects cancer dr




sometimes cells resist medication by spitting it back out. cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. researchers at the rockefeller university have shed new light on a molecular pump that makes this possible, by determining its ...



organ-on-a-chip model offers insights into premature aging and vascular disease




image: physiological strain induces a contractile phenotype in primary smooth muscle cells. view more credit: joao ribas, brigham and women's hospitalhutchinson-gilford progeria syndrome (hgps) is an extremely rare genetic condition that causes premature and accelerated aging. recently, researchers...



can math help explain our bodies -- and our diseases?




image: stephen smale, ph.d., and indika rajapakse, ph.d., have teamed up to create mathematical models that aim to explain how tissues emerge from the information contained in the genome. view more credit: university of michiganann arbor, mi - what makes a cluster of cells become a liver, or a musc...



can math help explain our bodies—and our diseases?




using advanced mathematics, researchers hope to create models of biological systems that can inform our understanding of normal development and disease. credit: university of michiganwhat makes a cluster of cells become a liver, or a muscle? how do our genes give rise to proteins, proteins to cells,...