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how cells pack tangled dna into neat chromosomes




how cells pack tangled dna into neat chromosomessign insubscribesearchsign inphotovideobackchannelmagazinewired insiderget our newsletterwired’s biggest stories delivered to your inbox.submitauthor: jordana cepelewiczjordana cepelewiczscience02.25.1807:00 amhow cells pack tangled dna into neat chr...



how cells pack tangled dna into neat chromosomes




how cells pack tangled dna into neat chromosomessign insubscribesearchsign inphotovideobackchannelmagazinewired insiderget our newsletterwired’s biggest stories delivered to your inbox.submitauthor: jordana cepelewiczjordana cepelewiczscience02.25.1807:00 amhow cells pack tangled dna into neat chr...



how cells pack tangled dna into neat chromosomes




how cells pack tangled dna into neat chromosomessign insubscribesearchsign inphotovideobackchannelmagazinewired insiderget our newsletterwired’s biggest stories delivered to your inbox.submitauthor: jordana cepelewiczjordana cepelewiczscience02.25.1807:00 amhow cells pack tangled dna into neat chr...



how cells pack tangled dna into neat chromosomes




how cells pack tangled dna into neat chromosomessign insubscribesearchsign inphotovideobackchannelmagazinewired insiderget our newsletterwired’s biggest stories delivered to your inbox.submitauthor: jordana cepelewiczjordana cepelewiczscience02.25.1807:00 amhow cells pack tangled dna into neat chr...



how cells combat chromosome imbalance




cambridge, ma -- most living cells have a defined number of chromosomes: human cells, for example, have 23 pairs. as cells divide, they can make errors that lead to a gain or loss of chromosomes, which is usually very harmful.for the first time, mit biologists have now identified a mechanism that th...



packing a genome, step-by-step




genome folding now has a playbook. a new step-by-step account spells out in minute-time resolution how cells rapidly pack long tangles of chromosomes into the tiny, tightly wound bundles needed for cell division. cells reel chromosomes into loops, and then wind the loops into spiral staircase struct...



'hail mary' mechanism can rescue cells with severely damaged chromosomes




the dna vital to the life of a cell is packaged in chromosomes, and a variety of checkpoints, repair mechanisms, and other cellular safeguards exist to maintain the integrity of the chromosomes during cell growth and division. those safeguards can fail, however, and a cell may find itself trying to ...



biologists discover the immune system can eliminate cells with too many or too f




chromosome segregation errors lead to abnormal karyotypes, a condition known as aneuploidy. shown here is a cell undergoing cell division and experiencing chromosome mis-segregation. credit: courtesy of the researchersmost living cells have a defined number of chromosomes: human cells, for example, ...



a protein duo ensures that the chromosomes in reproductive cells find their sign




reproduction is made easier by finding the right partner—and it's no different for the chromosomes inside reproductive cells. now, an international team of researchers, including a*star scientists, has revealed just how chromosomes find their perfect match. the tightly-wound chromosomes that carry...



researchers discover how human cells maintain the correct number of chromosomes




cell division is an essential process in humans, animals and plants as dying or injured cells are replenished throughout life. cells divide at least a billion times in the average person, usually without any problem. however, when cell division goes wrong, it can lead to a range of diseases, such as...



how chromosomes 'cheat' for the chance to get into an egg




each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. theoretically, when you create a gamete—a sperm or an egg—each copy has a 50-50 shot at being passed on. but the reality isn't so clearcut.



scientists reveal hidden structures in bacterial dna




dna contains the instructions for life, encoded within genes. within all cells, dna is organised into very long lengths known as chromosomes. in animal and plant cells these are double-ended, like pieces of string or shoelaces, but in bacteria they are circular. whether stringy or circular, these lo...



researchers discover how human cells maintain the correct number of chromosomes




image: the image shows rope-like structures called microtubules (in green) that capture chromosomes (in blue) at a highly specialized site called kinetochore (in red). microtubules impart mechanical forces that pull apart... view more credit: queen mary university of londoncell division is an esse...



'hail mary' mechanism can rescue cells with severely damaged chromosomes




the dna vital to the life of a cell is packaged in chromosomes, and a variety of checkpoints, repair mechanisms, and other cellular safeguards exist to maintain the integrity of the chromosomes during cell growth and division. those safeguards can fail, however, and a cell may find itself trying to ...



here’s the first 3d glimpse of how dna is packaged up in a single cell




enlarge/ intact genome from a mouse embryonic stem cell with 20 chromosomes colored differentlyuniversity of cambridge and mrc laboratory of molecular biologyshare this storyin a first, researchers have worked out a way to unravel and model the tangled, 3d structures of intact mammalian genomes from...



here’s the first 3d glimpse of how dna is packaged up in a single cell




enlarge/ intact genome from a mouse embryonic stem cell with 20 chromosomes colored differentlyuniversity of cambridge and mrc laboratory of molecular biologyshare this storyin a first, researchers have worked out a way to unravel and model the tangled, 3d structures of intact mammalian genomes from...



study shows liver cells with whole genome duplications protect against cancer




image: cri scientists find liver cells with whole genome duplications protect against cancer. view more credit: ut southwestern medical centerdallas - feb. 9, 2018 - researchers at the children's medical center research institute (cri) at ut southwestern have discovered that cells in the liver wit...



new study helps solve a great mystery in the organization of our dna




findings by benoit bruneau (left) and elphège nora (right) from the gladstone institutes reshape our understanding of how dna is organized in cells. credit: chris goodfellow, gladstone institutesafter decades of research aiming to understand how dna is organized in human cells, scientists at the gl...



counting chromosomes: plant scientists solve a century-old mystery about reprodu




counting is vital in nature. counting chromosomes is something that most animals, plants and even single-celled organisms need to know how to do to assure viability and to reproduce. today, a team of geneticists reveals a remarkable mechanism that enables plants to count their chromosomes, solving a...



chromosome motor discovery supports dna loop extrusion




it is one of the great mysteries in biology: how does a cell neatly distribute its replicated dna between two daughter cells? for more than a century, we have known that dna in the cell is comparable to a plate of spaghetti—a jumble of intermingled strands. when cells divide, they have to pack two...



new 3-d imaging reveals how human cell nucleus organizes dna and chromatin of it




image: chromatin structure determines the function of the human genome. to visualize chromatin of intact cells, a method called chromemt labels dna and paints a metal dust over chromatin. in the... view more credit: horng d. ou, salk institute.sixty-four years ago, james watson and francis crick d...



new 3-d imaging reveals how human cell nucleus organizes dna and chromatin of it




image: chromatin structure determines the function of the human genome. to visualize chromatin of intact cells, a method called chromemt labels dna and paints a metal dust over chromatin. in the... view more credit: horng d. ou, salk institute.sixty-four years ago, james watson and francis crick d...



the earliest stages of embryogenesis have been studied




for the first time, scientists from the faculty of biology of the lomonosov moscow state university in collaboration with their colleagues from austria and the usa have built up detailed maps of three-dimensional genome organization in individual cells and studied the characteristics of three-dimens...



dna discovery could help shed light on rare childhood disorder




credit: nihnew insights into how our cells store and manage dna during cell division could help point towards the causes of a rare developmental condition. the findings may also help researchers understand how genes are turned on in a process linked to cornelia de lange syndrome - a severe condition...



discovery of a novel chromosome segregation mechanism during cell division




researchers from japan used fission yeast to show that introns were involved in the promotion of heterochromatin structure formation. credit: associate professor tokio taniwhen cells divide, chromosomes need to be evenly segregated between daughter cells. this equal distribution of chromosomes is ve...