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first dna sequence from a single mitochondria




image: manual isolation of a single live mitochondria. the mitochondria can be seen under a microscope where a thin glass tube can be used to isolate the mitochondria from the dendrite... view more credit: jacqueline morris and jaehee lee, perelman school of medicine, university of pennsylvaniaphi...



animals' mitochondria defenses discovered in plants




arabidopsis thaliana plants used in this study. on the left is a plant under normal growth conditions, while on the right is a plant treated with doxycycline, which has significantly stunted its growth but is protected against aging as evidenced by its fresher appearance. credit: j. auwerx/epflmitoc...



breakthrough in understanding mitochondria | eurekalert! science news




image: ribosomes imaged on the surface of mitochondria by cryo-electron microscopy. view more credit: university of exeterscientists have made a breakthrough in understanding how mitochondria - the "powerhouses" of human cells - are made. mitochondria, which exist within human cells but have their...



accessing dna in the cell's powerhouse to treat disease




image: this is a schematic illustration of a mitochondria-specific dna-based synthetic ligand, called mito-pips that selectively read a target dna sequence and alter gene transcription. view more credit: kyoto university icemsfor the first time, a synthetic compound has been made that can bind to ...



accessing dna in the cell's powerhouse to treat disease




a schematic illustration of a mitochondria-specific dna-based synthetic ligand, called mito-pips that selectively read a target dna sequence and alter gene transcription. credit: kyoto university icemsfor the first time, a synthetic compound has been made that can bind to dna in the cells' energy po...



ucla biologists slow aging, extend lifespan of fruit flies




image: fruit flies' mitochondria (in green) at 10 days (top left), 28 days (top right) and 37 days old (both bottom images). at bottom right, the mitochondria have returned to a... view more credit: nature communications/anil ranaucla biologists have developed an intervention that serves as a cell...



a map of the cell's power station




image: the net-like structure of green colored mitochondria from the baker's yeast model organism. view more credit: source: ag meisingermitochondria are the cell's power stations; they transform the energy stored in nutrients so that cells can use it. if this function is disturbed, many different...



mitochondria behind blood cell formation




new northwestern medicine research published in nature cell biology has shown that mitochondria, traditionally known for their role creating energy in cells, also play an important role in hematopoiesis, the body's process for creating new blood cells.



a map of the cell's power station




the net-like structure of green colored mitochondria from the baker's yeast model organism. credit: source: ag meisingermitochondria are the cell's power stations; they transform the energy stored in nutrients for use by cells. if this function is disturbed, mitochondrial diseases can develop that o...



gastric cancer: a new strategy used by helicobacter pylori to target mitochondri




image: gastric tissue infected by h. pylori. nuclei are in blue (hoechst) and mitochondria in red (mitotracker labelling). view more credit: © laurent chatre - cnrs/institut pasteurhelicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's populati...



massive 3-d cell library teaches computers how to find mitochondria




using images of 6,000 stem cells, scientists have created the first-ever deep learning model to predict how cells are organized. the post massive 3-d cell library teaches computers how to find mitochondria appeared first on wired.



british scientists to create babies using 3 people's dna




(london) — britain's newcastle university says its scientists have received a license to create babies using dna from three people to prevent women from passing on potentially fatal genetic diseases to their children — the first time such approval has been granted.the license was granted thursda...



a new strategy used by helicobacter pylori to target mitochondria




gastric tissue infected by h. pylori. nuclei are in blue (hoechst) and mitochondria in red (mitotracker labelling). credit: laurent chatre - cnrs/institut pasteurscientists from the institut pasteur and cnrs have recently identified new strategies used by helicobacter pylori bacteria to infect cells...



mitochondrial protein in cardiac muscle cells linked to heart failure, study fin




image: dr. ming-hui zou, director of the center for molecular and translational medicine at georgia state university and a georgia research alliance eminent scholar in molecular medicine view more credit: georgia state universityatlanta--reducing a protein found in the mitochondria of cardiac musc...



stealing from the body: how cancer recharges its batteries




new research published today uncovers how the blood cancer 'steals' parts of surrounding healthy bone marrow cells to thrive, in work that could help form new approaches to cancer treatment in the future.researchers at the university of east anglia (uea), funded by the rosetrees trust and the big c ...



the bacteria responsible for legionellosis modulates the host cell metabolism to




image: legionella pneumophila (green), the bacterium responsible for severe acute lung disease inside eukaryotic cells. mitochondrial network in red, nucleus in blue. view more credit: © institut pasteur.intracellular pathogens adopt various strategies to circumvent the defences of the host cell ...



the bacteria responsible for legionellosis modulates the host cell metabolism to




legionella pneumophila (green), the bacterium responsible for severe acute lung disease inside eukaryotic cells. mitochondrial network in red, nucleus in blue. credit: © institut pasteur.scientists have shown that the bacterial pathogen legionella pneumophila has developed a specific strategy to ta...



technique for 'three-parent baby' revealed




details of a pioneering ivf technique using mitochondrial replacement therapy (mrt) have been revealed, giving hope to those families with inheritable mitochondrial disorders that they may be able to have healthy children in the future. the research and editorial, published in the journal reproducti...



dna of early neanderthal gives timeline for new modern human-related dispersal f




during excavations near the entrance of hohlenstein-stadel cave in southwestern germany in 1937 a 124,000 year old neanderthal femur was discovered. now its mitochondrial dna was analyzed and provides a timeline for a suggested migration of hominins out of africa before 220,000 years ago. credit: ©...



dna of early neanderthal gives timeline for new modern human-related dispersal f




ancient mitochondrial dna from the femur of an archaic european hominin is helping to resolve the complicated relationship between modern humans and neanderthals. the genetic data recovered by the research team, led by scientists from the max planck institute for the science of human history and the...



controlling energy production by calcium is an organ-specific affair




philadelphia (march 7, 2017) -- a heart beat begins with a rush of calcium into the heart cell followed by a burst of energy from the resident mitochondria. these two events occur with each beat. yet these events are not confined to heart cells and in fact occur in the cells of many other organs. a ...



nuclear transfer of mitochondrial dna in colon and rectal cancer




image: keshav singh. view more credit: uabbirmingham, ala. - patients with colon and rectal cancer have somatic insertions of mitochondrial dna into the nuclear genomes of the cancer cells, university of alabama at birmingham researchers report in the journal genome medicine.this study provides the...



research reveals how physical exercise protects the heart




regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.the benefits of exercise range from prevention of cachexia -severe loss of weight and muscle mass- and control of arterial blood pre...



common antiseptic ingredients de-energize cells and impair hormone response




a new in-vitro study by university of california, davis, researchers indicates that quaternary ammonium compounds, or "quats," used as antimicrobial agents in common household products inhibit mitochondria, the powerhouses of the cell, as well as estrogenic functions in cells. their findings will ap...



discovering what makes organelles connect could help understand neurodegenerativ




image: live-imaged hela cells with the endoplasmic reticulum labeled red and mitochondria labeled green. view more credit: images acquired by ginam cho.inside every cell is a complex infrastructure of organelles carrying out different functions. organelles must exchange signals and materials to ma...