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obesity: nonalcoholic fatty liver disease rising in u.s.




about 30% to 40% of american adults have a condition that has no visible signs and rarely causes symptoms, but can raise the risk of heart disease, diabetes, cirrhosis and liver cancer. it’s called nonalcoholic fatty liver disease—and as american waistlines continue to expand, the prevalence of ...



early-life bpa exposure reprograms gene expression linked to fatty liver disease




orlando--exposure during infancy to the common plasticizer bisphenol a (bpa) "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease (nafld) in adulthood. a new study has found how this process occurs, and researchers will present the results saturday...



george michael died of natural causes




a british coroner says george michael died of natural causes as the result of heart disease and a fatty liver. darren salter, senior coroner for oxfordshire, says a post-mortem has found that the singer died of "dilated cardiomyopathy with myocarditis and fatty liver."dilated cardiomyopathy is a co...



study: liver responds positively to leptin treatment in patients with lipodystro




ann arbor, mich. - researchers at michigan medicine have found the livers of patients with a rare disease that affects metabolism have responded positively to leptin therapy.in an open-label study, funded by the national institutes of health, the research team predicted the response of 23 patients w...



scientists watch fat metabolism in live fish, observe real-time lipid biochemist




a live image of the liver of a translucent, larval zebrafish. it was taken using confocal microscopy, which allows for clear images of the internal organs of a whole live animal. quinlivan fed a fluorescently tagged fatty acid to a larval zebrafish and then photographed its liver at 400x magnificati...



a novel molecular link between cholesterol, inflammation and liver cancer




hepatocellular carcinoma (hcc) is a deadly disease with no effective cure that develops in the context of liver diseases associated with chronic inflammation. a recent research article published in the journal of experimental medicine describes how important a protein called c-fos is for hcc develop...



the equine liver *h&h vip*




the equine liver looks similar to that in most other species. this smooth, dark red organ is situated near the front of the belly, between the lungs and the intestines. most of the liver is found on the right-hand side of the horse’s body, to allow room for the stomach on the left (see diagram, ab...



study: genetic markers may predict which hcv, cirrhosis patients improve with tr




chicago, il (may 6, 2017) -- genotyping of patients with advanced cirrhosis from hepatitis c virus could help health-care professionals predict the likelihood of improvement after successful hepatitis c treatment, thus minimizing the need for liver transplants. this study was presented at digestive ...



birth control for rats? don't laugh, it's a reality, and cities want it




one person died and two others fell ill last february in new york city after contracting leptospirosis, a disease caused by the bacteria leptospira. the bacteria are transmitted to humans through cattle, pigs, horses, dogs and, as in this case, rats. left untreated, leptospira can cause kidney damag...



liver fully recovers from a low protein diet




damage caused to the liver by a low protein diet can be repaired, a new study just published in the prestigious journal nutrition has found.during this study researchers from the school of veterinary medicine at the university of surrey in collaboration with the university of sao paulo examined the ...



why does the same exercise exert effects on individuals differently?




image: in patients with type-2 diabetes and in those with fatty liver, overproduced selenoprotein p exerts its effects on muscles through its binding to lrp1 receptor. selenoprotein p incorporated into muscles... view more credit: kanazawa university[background]in japan, due to the changes of lifes...



too many patients get liver tests they don't need, which can raise fears and cos




ann arbor, mich. - it can start with the quick check of a box. a doctor orders a range of blood tests all at once, hoping to figure out what's causing a patient to show signs of liver damage. it sounds harmless enough - and faster and more convenient than making the patient get more blood tests late...



researchers focus on cell membranes to develop alzheimer's treatments




ann arbor--thin parts of the cell membranes of neurons turn out to be particularly vulnerable to a protein that collects in the brain of people with alzheimer's disease, according to a university of michigan researcher. the discovery could open an avenue for developing treatments for alzheimer's dis...



use of opioid pain medications may affect liver transplant patients' survival




an analysis of nearly 30,000 patients undergoing liver transplantation in the united states between 2008 and 2014 found elevated death and organ loss rates in the first 5 years after transplantation among recipients with the highest use of opioid pain medications while on the waiting list.higher ris...



mouse epigenetic aging clock uncovered




credit: martha sexton/public domainageing in humans (and animals) can be seen as either an inevitable process of wear and tear or as an inherent biological programme by which the lifespan of each species is more or less predetermined. recent research has shown that dna methylation, an epigenetic mod...



thomas starzl: liver transplant pioneer dead at 90




transplant pioneer thomas starzl oversees a liver transplant operation at the university of pittsburgh medical center in pittsburgh, pa., on nov. 10, 1989. gene j. puskar—ap(pittsburgh) — dr. thomas starzl, the pioneer of liver transplantation and the driving force behind the world's first babo...



tick tock, stay ahead of the aging clock!




ageing in humans (and animals) can be seen as either an inevitable process of wear and tear or as an inherent biological programme by which the lifespan of each species is more or less predetermined. recent research has shown that dna methylation, an epigenetic modification which alters how dna is r...



new study: aggressive breast cancer grows faster in obese environment




it's not just what's inside breast cancer cells that matters. it's also the environment surrounding cancer cells that drives the disease, according to researchers at the university of north carolina lineberger comprehensive cancer center. in an abstract that will be presented april 3 at the american...



malaria parasites 'walk through walls' to infect humans




mosquitoes feed on blood meal at the insectary at the papua new guinea institute of medical research. credit: copyright mayeta clark 2015researchers have identified proteins that enable deadly malaria parasites to 'walk through cell walls' - a superpower that was revealed using the institute's first...



dr. thomas starzl, pioneer in baboon-to-human liver transplants, dies at 90




transplant pioneer thomas starzl oversees a liver transplant operation at the university of pittsburgh medical center in pittsburgh, pa., on nov. 10, 1989. gene j. puskar—ap(pittsburgh) — dr. thomas starzl, the pioneer of liver transplantation and the driving force behind the world's first babo...



new data shows avocado consumers have improved nutrient intakes




mission viejo, calif. (may 2, 2017) - a new analysis of the national health and nutrition examination survey (nhanes) data, compared avocado consumers to non-consumers and found that consuming avocados may be associated with an overall better diet, higher intake of essential nutrients, lower body we...



liver tumor growth in mice slowed with new chemo-immunotherapy treatment




image: university of missouri school of medicine researchers have developed a new treatment that combines chemotherapy and immunotherapy to significantly slow tumor growth in mice. the team includes (from left) guangfu... view more credit: justin kelley/mu healthcolumbia, mo. (feb. 28, 2017) -- hep...



berlin baby polar bear fritz dies following liver failure




the first baby polar bear born at a berlin zoo in over two decades died suddenly earlier this week.fritz, who was born at the tierpark berlin this past november, died of liver inflammation, according to an explanation on the zoo's website.the 4-month-old baby bear was found listless in his den on mo...



ubc researchers connect common fats to a lazy lifestyle and diabetes




image: ubc researcher sanjoy ghosh connects common fats to a lazy lifestyle and diabetes. view more credit: ubc okanagana ubc researcher is suggesting the types of cooking oils people consume may be sabotaging their efforts to stay healthy and avoid illnesses such as diabetes. sanjoy ghosh, a micha...



research suggests bans on trans fats linked to healthier communities




people living in areas that restrict trans fats in foods had fewer hospitalizations for heart attack and stroke compared to residents in areas without restrictions, according to a new study conducted by researchers at the university of chicago medicine and yale school of medicine."the results are im...