Laxaro

View the latest news and breaking news today

boosting t cell memory may result in longer lasting and effective responses for patients - Search

boosting t cell memory may result in longer lasting and effective responses for patients Searched from official sources arount the web with simple content and resource link From any languages in different countries.



boosting t cell 'memory' may result in longer-lasting and effective responses fo




image: this is stephen mok, ph.d. view more credit: md anderson cancer centerjust like people, some t cells have excellent memories. these subtypes known as memory t cells may explain why some immunotherapies are more effective than others and potentially lead to researchers designing more effecti...



new strategy to target transcription factor stat5 to combat leukaemia




the term „hematopoietic cancer" refers to several, in most cases quite severe health conditions in which the process of blood cell production is altered. cancers of white blood cells are characterized by enhanced proliferation and reduced differentiation and cell death in one myeloid lineage, whic...



is whole-brain radiation still best for brain metastases from small-cell lung ca




image: chad rusthoven, m.d., and university of colorado cancer center colleagues show promise of targeted radiation against brain metastases from small-cell lung cancer. view more credit: university of colorado cancer centerlung cancer often metastasizes to the brain. historically, brain metastase...



cd4+ t-cell count useful to assess antiretroviral therapy response in htlv-1/hiv




the authors compared the cd4+ t-cell counts and hiv-1 rna viral loads of 383 patients who were either mono-infected with hiv or co-infected with htlv-1/hiv. they confirmed that co-infected patients were more likely to have higher cd4+ t-cell counts prior to treatment initiation with no immunologic b...



specialized blood vessels enhance tumor-fighting immunotherapy




scientists from vib and ku leuven, together with colleagues from the university of california and the swiss institute for experimental cancer research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments. the successful combination of these two therapies results in ...



drug combination shows better tolerance and effectiveness in metastatic renal ce




lebanon, n.h. - a new cooperative research study including norris cotton cancer center's lionel lewis, mb bch, md, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with...



mystery of memory cells answered through mouse study




image: researchers from the university of missouri school of medicine have identified a molecular mechanism that operates in memory t cells that could be manipulated to produce and maintain more memory... view more credit: mu healthcolumbia, mo. (march 13, 2017) -- when an infection attacks the bod...



2d material integrates digital logic and memory into one chip




researchers at stanford university have demonstrated that field-effect transistors made from a single layer of molybdenum disulfide (mos2) can successfully drive resistive random access memory. the results, which were reported last week at the ieee international electron devices meeting, represen...



phase 2 car-t study reports significant remission rates at 15-month follow up




image: this is sattva neelapu, m.d. view more credit: md anderson cancer centera study involving the recently approved cd19-targeting chimeric antigen receptor (car) t cell therapy shows that 42 percent of patients with aggressive large b-cell lymphoma remained in remission at 15 months following ...



personalized tumor vaccine shows promise in pilot trial




philadelphia - a new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the perelman school of medicine at the university of pennsylvania and the abramson cancer center of the university of pennsylvania. the personalized vaccine is made from patients' own ...



stem-cell transplants show limited benefit for double-hit lymphoma patients in r




image: this is daniel j. landsburg, m.d. view more credit: penn medicinephiladelphia - patients with double hit lymphoma (dhl) who undergo autologous stem-cell transplantation (autosct) after achieving remission are not more likely to remain in remission or live longer than patients who do not und...



'educating' patients' immune cells may help combat diabetes




new research reveals that a treatment called stem cell educator therapy is safe and effective for treating type 1 and type 2 diabetes. the therapy cultures the patient's immune cells with cord blood stem cells and returns only the "educated" immune cells to the patient's circulation.the strategy may...



flu may cause brain health changes lasting weeks after infection




as if the flu isn’t scary enough, a new study highlights a potential concern beyond body aches and chills: brain health changes. according to a newly published study, certain influenza strains resulted in brain health changes in mice, including to memory, the effects of which lasted weeks after in...



study explores use of checkpoint inhibitors after relapse from donor stem cell t




atlanta - immunotherapy agents known as checkpoint inhibitors have shown considerable promise in patients with hematologic cancers who relapse after a transplant with donor stem cells. preliminary results from the first clinical trial in these patients of one such agent - nivolumab - indicate that a...



molecular therapy set to protect at-risk patients against heart attack and strok




even a single dose of a specific ribonucleic acid molecule, known as a small interfering rna (sirna), offers patients at high risk of cardiovascular disease long-lasting protection against high ldl cholesterol - one of the main risk factors for heart attack and stroke. this is the result of a clinic...



flies the key to studying the causes of dementia




a research team from the university of plymouth, university of southampton and the alexander fleming biomedical sciences research center, vari, greece, have studied two structurally-similar proteins in the adult brain and have found that they play distinct roles in the development of dementia.their ...



studies reveal how shingles vaccine should be used in arthritis patients




new research indicates that the live varicella-zoster vaccine--which is given to protect against shingles--elicits robust immune responses in patients when administered several weeks prior to the start of treatment with the arthritis drug tofacitinib. the arthritis & rheumatology findings are encour...



beta blockers may boost immunotherapy, help melanoma patients live longer




hershey, pa. -- a common, inexpensive drug that is used to prevent heart attacks and lower blood pressure may also help melanoma patients live longer, according to researchers.researchers at penn state found that melanoma patients who received immunotherapy while taking a specific type of beta block...



scleroderma study: hope for a longer life for patients with rare autoimmune diso




image: researcher karen ballen, md, director of stem cell transplantation at the university of virginia cancer center, calls the scleroderma findings a "major advance. " view more credit: uva health systeman unusual autoimmune disease that causes skin and lung damage can be treated effectively by ...



prevention and prediction: understanding how lung cancer progresses




philadelphia - treating the brain with a preventative course of radiation may help small cell lung cancer (sclc) patients - whose tumors often spread to their brain -- live longer, according to a new study from researchers in the abramson cancer center and perelman school of medicine at the universi...



mechanism identified of impaired dendritic cell function that weakens response t




philadelphia -- (dec. 14, 2017) -- a new study from the wistar institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (dcs), a specialized type of immune cells that expose the antigens on their surface to activate the t cells. the new findings expla...



thorough analysis reveals immune system dynamics after immunotherapy




by combining new system-biological analyses and advanced data analysis, researchers at karolinska institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation. the technique, which reveals complex interactions bet...



study shows white blood cell boosting drugs safe during chemo-radiotherapy of lu




geneva, switzerland, may 5, 2017 - a late breaking subanalysis of the phase iii convert trial presented at the european lung cancer conference (elcc) shows that white blood cell boosting drugs are safe during concurrent chemo-radiotherapy of small cell lung cancer (sclc).1"the optimal treatment for ...



cell-weighing method could help doctors choose cancer drugs




cambridge, ma - doctors have many drugs available to treat multiple myeloma, a type of blood cancer. however, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. this can lead to months of treatment with a drug that isn't working.researcher...



new device for low-cost single-cell analysis identifies fibroblast subtypes in r




image: researchers at the new york genome center (nygc) and new york university (nyu) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-d-printed, portable and low-cost... view more credit: new york genome centernew york, ny (feb. 23, 2018) - single-cell analy...