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organ-on-a-chip model offers insights into premature aging and vascular disease

organ-on-a-chip model offers insights into premature aging and vascular disease Article News With Simple Text and Web Resource Link. For View Full Content Click on Source Link on Then Bottom Of News.



organ-on-a-chip model offers insights into premature aging and vascular disease

photograph of the microfluidic channel showing the media inlet and outlet. credit: joao ribas, brigham and women's hospitalhutchinson-gilford progeria syndrome (hgps) is an extremely rare genetic condition that causes premature and accelerated aging. recently, researchers have been able to generate induced pluripotent stem cells from patients with hgps to better understand the mechanisms of aging and look for new treatments. hgps primarily affects vascular cells, which undergo biomechanical strains in blood vessels. however, the impact of these biomechanical strains on aging and vascular diseases has been challenging to study in the lab as most models fail to mimic the biomechanics that ce...