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nejm publishes final results from phase two study showing vaccines can reduce rate of sustained tb infections

nejm publishes final results from phase two study showing vaccines can reduce rate of sustained tb infections Article News With Simple Text and Web Resource Link. For View Full Content Click on Source Link on Then Bottom Of News.



nejm publishes final results from phase two study showing vaccines can reduce rate of sustained tb infections

rockville, maryland (july 11, 2018) --aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (tb), today announced the publication of the full results from a phase 2, randomized, controlled clinical trial of two tb vaccines-- the currently available bcg vaccine and an investigational vaccine, h4:ic31--in the new england journal of medicine (nejm). this proof-of-concept study showed that vaccination can reduce the rate of sustained tb infections in a high-transmission setting, such as in uninfected, healthy adolescents in the western cape of south africa where the study was conducted. in the trial, revaccination with bcg significantly reduced sustained tb infections in adolescents with a 45.4% vaccine efficacy. ...