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inflammatory factors linked to inhibition of factor viii gene therapy in hemophilia a

inflammatory factors linked to inhibition of factor viii gene therapy in hemophilia a Article News With Simple Text and Web Resource Link. For View Full Content Click on Source Link on Then Bottom Of News.



inflammatory factors linked to inhibition of factor viii gene therapy in hemophilia a

image: human gene therapy presents reports on the transfer and expression of genes in mammals, including humans. view more credit: mary ann liebert, inc., publishersnew rochelle, ny, december 7, 2017--as a gene therapy cure for hemophilia a moves closer to reality, a new study sheds light on a challenging complication in which a host autoimmune response inhibits the production of normal clotting factor viii from the transferred fviii gene. researchers compared the levels of multiple pro- and anti-inflammatory cytokines in a mouse model of hemophilia a that received fviii gene therapy at different ages and either did or did not exhibit fviii inhibitor formation, as presented in an article published in human gene therapy, a peer-reviewed ...