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tweaking muscle metabolism prevents obesity and diabetes in mice

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tweaking muscle metabolism prevents obesity and diabetes in mice

mildly stressing muscle metabolism boosts levels of a beneficial hormone that prevents obesity and diabetes in mice, according to a new study by researchers at the university of iowa.the new findings, published in the embo journal, show that triggering a certain type of metabolic stress in mouse muscle cells causes them to produce and secrete significant amounts of the anti-diabetic hormone called fibroblast growth factor-21 (fgf21), which then has widespread beneficial effects on whole-body metabolism. the mice in the experiments were completely protected from obesity and diabetes that normally develop due to aging or eating a high-fat diet. moreover, triggering the fgf21 production after...